The CBF manufactures vaccines and gene therapy products that are based on human or chimpanzee adenovirus backbones. The disease areas include malaria, tuberculosis, HIV, flu, hepatitis C and cancer. 17 adenovirus products have been manufactured for clinical trials directly or for further processing by third parties. As well as manufacturing IMPs, the CBF also imports, labels and certifies vaccines and gene therapy products for clinical trials.
The first product, AdCh63 ME-TRAP, was produced in three separate batches in 2007, 2010 and 2011, with the last batch size being over 2000 vials.
The following timeline shows all products/batches of viral vector vaccines and gene therapy products manufactured to date: